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Factor I Deficiency

Factor I (1) or fibrinogen deficiency is an inherited bleeding disorder caused when a person’s body does not produce any or enough of a protein in the blood (fibrinogen) that plays an important role in blood clotting or the fibrinogen doesn’t work properly. It is very rare and often found in people whose parents are blood relatives.

Links to selected resources:

Factor I (Fibrinogen) Deficiency
(World Federation of Hemophilia, 2023)
Explains the causes of Factor I deficiency, its symptoms, diagnosis and treatment.

Factor I deficiency (Fibrinogen deficiency)
(Canadian Hemophilia Society, 2004)
A comprehensive booklet covering types of fibrinogen deficiency, causes, inheritance, symptoms, treatments, prevention, special precautions and specific problems for women.

Factor I deficiency
(National Hemophilia Foundation, USA)

Source: What are rare clotting factor deficiencies? World Federation of Hemophilia, Montreal, Canada, 2023.

NB We provide these links as a service to the haemophilia community. As web sites can change or should you find a site to be no longer active please notify hfaust@haemophilia.org.au. Haemophilia Foundation Australia is not responsible for the content of any external web sites. The featuring of a site on this page is not an endorsement by HFA of the information or views expressed therein.

Date last reviewed: 1 February 2024

Important Note: This information was developed by Haemophilia Foundation Australia for education and information purposes only and does not replace advice from a treating health professional. Always see your health care provider for assessment and advice about your individual health before taking action or relying on published information. This information may be printed or photocopied for educational purposes.

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