Factor XI Deficiency
Factor XI (11) deficiency, also known as haemophilia C, is an inherited bleeding disorder. It is caused when a person's body doesn't produce enough of protein in the blood (factor XI or FXI) that helps blood clot or the factor XI doesn’t work properly. Unlike haemophilia A or B, there is no bleeding into joints and muscles.
Factor XI deficiency is the most common of the rare bleeding disorders, estimated at one in 100,000 people, and is the third most common bleeding disorder to affect women after von Willebrand disease and haemophilia.
Links to selected resources:
What Is Factor XI Deficiency?
(World Federation of Hemophilia)
See the About Bleeding Disorders section. Explains the causes of this blood disorder, its symptoms, diagnosis and treatment.
Factor XI deficiency (Hemophilia C)
(Canadian Hemophilia Society)
Explains factor XI deficiency, what causes it, how it is passed on, how common it is, diagnosis, symptoms and treatments.
Factor XI deficiency
(National Hemophilia Foundation, USA)
Pre-pregnancy planning if you have factor XI deficiency
(Factored In, HFA)
Source: What are rare clotting factor deficiencies? World Federation of Hemophilia: Montreal, 2009.
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Date last reviewed: 3 November 2021